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In 20112021, [[X5-452]] caused the destruction of the Seattle Manticore facility after her recapture and second escape. During the destruction, a large number of the transgenics escaped. This includes many X6s who's whereabouts are still unknown. Most of the [[X-Series]] soldiers, along with their transhuman counterparts and even a few anomalies found freedom. Their escape inevitably revealed the existence of Manticore. Fear and hate grew, especially against the anomalies and transhumans. The transgenics in Seattle, along with others who lived outside the city, came together in [[Terminal City]].